Author: Duran Kala1
1Ishik University, Erbil, Iraq
Abstract: The paper describes pharamacolgical properties of therapeutic plants Matricaria chamomilla,is referred to as chamomile or German chamomile. It is used in folk medicine and in modern medicine as therapeutic plant in the thearapy of upper respiratory infections and various disorders. Chamomile can live in large areas in nature. Every herbal plant has cytotoxic effects. In determination of any possible cytotoxic effects of Matricaria chamomilla, extracts on HeLa CEACAM cells, serial solutions (1/10, 1/50, 1/100, 1/1000, ) of Matricaria chamomilla, extracts were incubated with HeLa CEACAM cells for 24 and 48 h. The cell viability was calculated by the tetrazolium salt 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Matricaria chamomilla, plant extracts showed toxic effect at 1/10 solution, however toxicity of the extracts definitely decreased at 1/50 solution for 24 and 48 hours. Results suggested that the cytotoxic effect of Matricaria chamomilla extracts were concentration dependent but not timedependent in that less cells were viable at 1/10 solution compared to 1/1000 solution. According to results, the plant extract solution of 1/1000 was calculated as an effective dose for future researches
Keywords: Chamomile, Matricaria Chamomilla, HeLa CEACAM, Cytotoxcity, MTT, Cancer
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International Journal of Social Sciences & Educational Studies
ISSN 2409-1294 (Print), June 2014, Vol.1, No.4